Postdoctoral Scientist - Antibody-RNA Conjugation, Genetic Medicine at Eli Lilly and Company

Boston, Massachusetts, United States

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Not SpecifiedCompensation

Entry Level & New GradExperience Level

Full TimeJob Type

UnknownVisa

Pharmaceuticals, BiotechnologyIndustries

Requirements

Ph.D. in synthetic chemistry, chemical biology, or related scientific field with all completed requirements by September 2025
Extensive knowledge of cutting-edge modern organic chemistry, linker design and complex molecule synthesis
Understanding advanced analytical and purification techniques
Experience in antibody-drug conjugates and/or oligonucleotide chemistry (preferred)
Proficiency in independently executing research tasks
High learning agility in the field of new scientific concepts and drug modalities
Strong problem-solving skills with creative solutions in constructing complex molecular systems
A proven track record of significant contributions to research projects, substantiated by first or co-authorship on peer-reviewed scientific publications
A track record of productive collaborations in interdisciplinary team environment
Excellent communication and organizational skills
Strong background in synthetic organic chemistry and experience in molecular design

Responsibilities

Develop novel linker strategies for antibody-RNA conjugates and bioconjugation methodologies
Design and synthesize novel linkers for controlled drug release
Collaborate closely with ADME teams to develop robust bioanalytical methods and to investigate PK/PD relationships for antibody-RNA conjugates
Contribute to optimization of internal antibody-RNA conjugate workflow
Work productively and safely in the laboratory; and maintain good practice in writing experimental reports in an electronic lab notebook
Communicate experimental results and project progress with supervisor and at team/department meetings
Publish/share original research externally (presentations, peer-reviewed articles, and conferences)

Skills

Synthetic Organic Chemistry

Molecular Design

Linker Synthesis

Drug Conjugates

Antibody-RNA Conjugation

Extrahepatic Delivery

Characterization

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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