Master Thesis: Interference of Therapeutic Antibodies in Olink Biomarker Assays at Thermo Fisher Scientific

Uppsala, Uppsala County, Sweden

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Not SpecifiedCompensation

InternshipExperience Level

InternshipJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

Currently pursuing a master’s degree in biotechnology, biomedicine, molecular biology, or a related field
Interested in bioanalysis, proteomics, and pharmaceutical research
Enjoy combining experimental work with data analysis and problem-solving
Available for full-time on-site work in Uppsala, Sweden from Jan–June 2026 (Mon-Fri schedule)
Able to work in an environment requiring some degree of PPE (e.g., safety glasses, gowning, gloves, lab coat, ear plugs)

Responsibilities

Test a selection of known therapeutic antibodies in plasma (spike-in) and analyze interference using mid-plex PEA readouts (Screening)
Perform titrations for selected antibodies and investigate detailed effects (Deep Dive)
For selected cases, verify interactions using SPR (Surface Plasmon Resonance) technology (Mechanistic Studies)
Optional (time permitting): Explore and compare with plasma samples endogenously treated with therapeutic antibodies based on assay signatures

Skills

Olink PEA

Proximity Extension Assay

SPR

Surface Plasmon Resonance

Bioanalysis

Proteomics

Biophysical Methods

Plasma Analysis

Biomarker Assays

Data Analysis

Thermo Fisher Scientific

Provides life sciences products and services

About Thermo Fisher Scientific

Thermo Fisher Scientific offers a variety of products and services that support scientific research and healthcare, including laboratory equipment, reagents, and software solutions. Their products are used in applications like protein biology, real-time PCR, and sequencing, serving clients such as academic institutions and pharmaceutical companies. Unlike competitors, Thermo Fisher emphasizes customer support and education, helping clients optimize their experiments. The company's goal is to be a leading provider of life sciences solutions that contribute to a healthier and safer world.

Waltham, MassachusettsHeadquarters

1956Year Founded

$17MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Increased competition in single-use bioprocessing may impact market share.

Sale of anatomical pathology business could create a temporary product gap.

Investment in miDiagnostics may face regulatory challenges affecting returns.

Differentiation

Thermo Fisher offers a comprehensive range of life sciences products and services.

Their well-known brands include Thermo Scientific, Applied Biosystems, and Invitrogen.

They provide strong customer support and educational resources to optimize client workflows.

Upsides

Expansion of biologics production facility enhances capacity for precision biologics monitoring.

Investment in miDiagnostics aligns with demand for rapid diagnostic solutions in BioPharma.

Collaboration with Mainz Biomed positions them in the growing cancer detection market.

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