Instrument Software Engineer at Twist Bioscience

South San Francisco, California, United States

Twist Bioscience Logo
Not SpecifiedCompensation
Mid-level (3 to 4 years)Experience Level
Full TimeJob Type
UnknownVisa
Biotechnology, ManufacturingIndustries

Requirements

  • BS in Computer Science or related field with 3+ years of working experience; or 1 year and a Master's degree; or five years of relevant experience with a BS; or three years of experience with a Master's degree in Computer Science or related field
  • Proficient in C#, WPF, and UX
  • Extensive background with electro-mechanical systems and instrumentation
  • Familiar with Agile and software development lifecycle
  • Experience with Visual Studio, Git, Jira, and Azure (nice to have)
  • Good understanding of software design principles
  • Knowledgeable in scientific computation and data analysis
  • Hands-on experience with lab instrumentation and integrated systems
  • Excellent communication and writing skills, and ability to work in a fast-paced team environment
  • Experience with LIMS (Laboratory Information Management System) and MES (Manufacturing Execution System) is a strong plus

Responsibilities

  • Design, implement, and maintain software that controls and communicates with laboratory instruments
  • Develop user interfaces, data acquisition modules, hardware abstraction layers, and real-time control logic
  • Sustain and troubleshoot existing instrument software used in production environments
  • Collaborate with hardware, electrical, mechanical, and systems engineers to ensure seamless integration between software and hardware components
  • Develop and support communication protocols (e.g., USB, RS-232, CAN, TCP/IP) for instrument control and data exchange
  • Provide ongoing software support for deployed instruments, especially in manufacturing and lab environments
  • Investigate and resolve bugs, performance issues, and integration failures in collaboration with the support and testing teams
  • Work with test engineers to develop and execute verification and validation protocols to ensure software reliability and compliance
  • Support automated and manual testing of instrument software, including regression testing
  • Write and maintain detailed technical documentation, including design specifications, software architecture, and user manuals
  • Ensure software complies with applicable regulatory standards (e.g., FDA, ISO 13485, if applicable)
  • Contribute to research and development efforts for next-generation instruments
  • Evaluate new technologies, frameworks, and methodologies to improve instrument performance and usability
  • Work closely with scientists, lab personnel, manufacturing teams, and field service engineers to gather feedback and implement improvements
  • Participate in design reviews and product development meetings to align software solutions with business and user needs

Skills

C++
Python
USB
RS-232
CAN
TCP/IP
MES
User Interfaces
Data Acquisition
Hardware Abstraction
Real-time Control
Troubleshooting
Testing
Technical Documentation

Twist Bioscience

Produces synthetic DNA for biotechnology applications

About Twist Bioscience

Twist Bioscience specializes in creating synthetic DNA for applications in biotechnology, pharmaceuticals, and research. Their proprietary platform allows for the quick and accurate production of DNA sequences, providing clients with products like genes, oligo pools, and variant libraries. The company stands out by offering high-quality DNA at competitive prices, making them a valuable partner for academic institutions and pharmaceutical companies. Twist Bioscience aims to support advancements in personalized medicine and biotechnology through their innovative DNA synthesis solutions.

South San Francisco, CaliforniaHeadquarters
2013Year Founded
$236.5MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
1,001-5,000Employees

Benefits

Health Insurance
Dental Insurance
Vision Insurance
Disability Insurance
Life Insurance
401(k) Retirement Plan

Risks

Increased competition from Ginkgo Bioworks may impact Twist's market share.
Dependency on AI technologies could pose integration and operational challenges.
New CIO appointment may lead to transitional challenges in IT strategy and operations.

Differentiation

Twist Bioscience uses a unique silicon-based DNA synthesis platform for precision and scale.
They offer high-quality DNA sequences at competitive prices, attracting diverse clients.
Their proprietary platform provides instant feedback on DNA sequence synthesis feasibility.

Upsides

Growing demand for synthetic DNA in personalized medicine boosts Twist's market potential.
Collaboration with Absci leverages AI to accelerate antibody discovery and drug development.
Synthetic biology market projected to grow at 28.8% CAGR, benefiting Twist's growth.

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