Instrument Software Engineer at Twist Bioscience

South San Francisco, California, United States

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Not SpecifiedCompensation

Mid-level (3 to 4 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, ManufacturingIndustries

Requirements

BS in Computer Science or related field with 3+ years of working experience; or 1 year and a Master's degree; or five years of relevant experience with a BS; or three years of experience with a Master's degree in Computer Science or related field
Proficient in C#, WPF, and UX
Extensive background with electro-mechanical systems and instrumentation
Familiar with Agile and software development lifecycle
Experience with Visual Studio, Git, Jira, and Azure (nice to have)
Good understanding of software design principles
Knowledgeable in scientific computation and data analysis
Hands-on experience with lab instrumentation and integrated systems
Excellent communication and writing skills, and ability to work in a fast-paced team environment
Experience with LIMS (Laboratory Information Management System) and MES (Manufacturing Execution System) is a strong plus

Responsibilities

Design, implement, and maintain software that controls and communicates with laboratory instruments
Develop user interfaces, data acquisition modules, hardware abstraction layers, and real-time control logic
Sustain and troubleshoot existing instrument software used in production environments
Collaborate with hardware, electrical, mechanical, and systems engineers to ensure seamless integration between software and hardware components
Develop and support communication protocols (e.g., USB, RS-232, CAN, TCP/IP) for instrument control and data exchange
Provide ongoing software support for deployed instruments, especially in manufacturing and lab environments
Investigate and resolve bugs, performance issues, and integration failures in collaboration with the support and testing teams
Work with test engineers to develop and execute verification and validation protocols to ensure software reliability and compliance
Support automated and manual testing of instrument software, including regression testing
Write and maintain detailed technical documentation, including design specifications, software architecture, and user manuals
Ensure software complies with applicable regulatory standards (e.g., FDA, ISO 13485, if applicable)
Contribute to research and development efforts for next-generation instruments
Evaluate new technologies, frameworks, and methodologies to improve instrument performance and usability
Work closely with scientists, lab personnel, manufacturing teams, and field service engineers to gather feedback and implement improvements
Participate in design reviews and product development meetings to align software solutions with business and user needs

Skills

Key technologies and capabilities for this role

C++PythonUSBRS-232CANTCP/IPMESUser InterfacesData AcquisitionHardware AbstractionReal-time ControlTroubleshootingTestingTechnical Documentation

Questions & Answers

Common questions about this position

Is this role remote or onsite?

This is an onsite role in South San Francisco, California.

What are the required qualifications for this position?

Candidates need a BS in Computer Science or related field with 3+ years of experience, or equivalent with a Master's degree, plus proficiency in C#, WPF, and UX, and extensive background with electro-mechanical systems.

What programming skills are required for this role?

Proficiency in C#, WPF, and UX is required.

What is the salary range for this position?

This information is not specified in the job description.

What qualities make a strong candidate for this role?

A self-motivated, fast-learning, and detail-oriented engineer with strong familiarity in lab instrumentation and a passion for building reliable, scalable systems is ideal.

Twist Bioscience

Produces synthetic DNA for biotechnology applications

About Twist Bioscience

Twist Bioscience specializes in creating synthetic DNA for applications in biotechnology, pharmaceuticals, and research. Their proprietary platform allows for the quick and accurate production of DNA sequences, providing clients with products like genes, oligo pools, and variant libraries. The company stands out by offering high-quality DNA at competitive prices, making them a valuable partner for academic institutions and pharmaceutical companies. Twist Bioscience aims to support advancements in personalized medicine and biotechnology through their innovative DNA synthesis solutions.

South San Francisco, CaliforniaHeadquarters

2013Year Founded

$236.5MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

1,001-5,000Employees

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Disability Insurance

Life Insurance

401(k) Retirement Plan

Risks

Increased competition from Ginkgo Bioworks may impact Twist's market share.

Dependency on AI technologies could pose integration and operational challenges.

New CIO appointment may lead to transitional challenges in IT strategy and operations.

Differentiation

Twist Bioscience uses a unique silicon-based DNA synthesis platform for precision and scale.

They offer high-quality DNA sequences at competitive prices, attracting diverse clients.

Their proprietary platform provides instant feedback on DNA sequence synthesis feasibility.

Upsides

Growing demand for synthetic DNA in personalized medicine boosts Twist's market potential.

Collaboration with Absci leverages AI to accelerate antibody discovery and drug development.

Synthetic biology market projected to grow at 28.8% CAGR, benefiting Twist's growth.

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