Senior Scientist I, Drug Product and Device Development at Vir Biotechnology

San Francisco, California, United States

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Not SpecifiedCompensation

Senior (5 to 8 years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

PhD with 5+ years, Master’s with 8+ years’, or Bachelor’s with 10+ years’ experience in Biosciences, Pharmaceutical Technology, Biochemistry, Chemistry, Chemical Engineering, or a related discipline
Demonstrated expertise in formulation and drug product development for monoclonal antibodies and biologics (required); hands-on experience with lyophilization and prefilled syringe development (strongly preferred)
Proficiency in experimental design (DoE), data analysis, and use of statistical programs for formulation screening and optimization
Strong working knowledge of analytical methods supporting formulation development

Responsibilities

Provide scientific leadership of formulation development and process optimization for parenteral dosage forms of monoclonal antibodies and biologics, ensuring robustness, stability, and scalability
Design and execute in-house laboratory studies, including formulation screening, in-use stability studies, and analytical characterization, leveraging advanced experimental designs (DoE) and statistical methods
Provide technical direction and oversight for internal and external drug product development and manufacturing activities, including data review, trouble-shooting, and risk assessment
Lead technical transfer of manufacturing processes at contract manufacturing organizations, managing cross-functional alignment and proactively addressing challenges
Author and review high-impact technical reports, regulatory submissions, and scientific publications, ensuring clarity, accuracy, and regulatory compliance
Represent Drug Product and Formulation and Device Development on cross-functional program teams, actively contributing to strategy, timelines, and issue resolution in collaboration with clinical, process development, analytical, quality, and regulatory stakeholders
Ensure consistent scientific oversight for data generated by internal teams and contract research/manufacturing organizations, upholding best practices and industry standards
Drive continuous improvement initiatives and implement new technologies or methodologies to strengthen group capabilities

Skills

Key technologies and capabilities for this role

Formulation DevelopmentLyophilized FormulationsLiquid FormulationsBiologic ModalitiesProcess OptimizationParenteral Dosage FormsDrug Product DevelopmentDevice DevelopmentProcess DevelopmentManufacturing SupportMonoclonal Antibodies

Questions & Answers

Common questions about this position

Is this role remote or does it require office presence?

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

What are the key responsibilities of this Senior Scientist I position?

The role involves scientific leadership of formulation development and process optimization for biologics, designing and executing lab studies using DoE and statistical methods, providing technical oversight for development and manufacturing, leading tech transfers, authoring reports, and representing Drug Product on cross-functional teams.

What is the reporting structure for this position?

This person will report to the Senior Director, Drug Product Process and Formulation.

What is the company culture like at Vir Biotechnology?

Vir Biotechnology is committed to creating a company where everyone feels supported and encouraged to give their best, believing that the success of colleagues drives the success of the mission.

What makes a strong candidate for this Senior Scientist I role?

A strong candidate will have technical leadership experience in developing liquid and lyophilized formulations for biologics, expertise in DoE and statistical methods for lab studies, and the ability to collaborate cross-functionally while managing internal and external projects.

Vir Biotechnology

Develops monoclonal antibodies for infectious diseases

About Vir Biotechnology

Vir Biotechnology develops treatments that leverage the immune system to combat infectious diseases. The company uses a proprietary monoclonal antibody platform combined with machine learning to create a database of human antibodies, which aids in developing effective medicines. Their pipeline includes candidates for hepatitis B, hepatitis delta, HIV, and various viruses like influenza and COVID-19. Vir stands out by collaborating with industry leaders and organizations to accelerate scientific advancements, with the goal of transforming lives through innovative therapies.

San Francisco, CaliforniaHeadquarters

2016Year Founded

$640.6MTotal Funding

IPOCompany Stage

AI & Machine Learning, Biotechnology, HealthcareIndustries

501-1,000Employees

Benefits

Comprehensive healthcare coverage

Employer matched 401(k)

Employee stock purchase plan

Childcare assistance

Tuition reimbursement

Risks

Leadership instability due to key executive resignations may disrupt operations.

Job cuts and facility closures indicate potential financial strain.

Struggles to diversify beyond COVID-19 antibody success may impact revenue growth.

Differentiation

Vir Biotechnology uses AI-enhanced capabilities for monoclonal antibody development.

The company focuses on immune system manipulation for targeted therapies.

Vir's pipeline includes a potential functional cure for chronic hepatitis B.

Upsides

Increased interest in AI-driven drug discovery benefits Vir's AI capabilities.

The rise of personalized medicine aligns with Vir's monoclonal antibody focus.

Global pandemic preparedness funding supports Vir's broad-spectrum antiviral therapies.

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