Principal Scientist/Sr. Principal Scientist Molecular Biology, Cell Culture Upstream Process Development at Eli Lilly and Company

Indianapolis, Indiana, United States

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Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, PharmaceuticalsIndustries

Requirements

BS/MS in Microbiology, Cell Biology, Molecular Biology, Biology, Chemical Engineering, or related field
BS with >6 years or MS with >3 years of relevant industrial experience
Ability to work well in a team environment incorporating a variety of functional relationships and desire to be a point of accountability
Effective oral and written communication skills, self-management, task planning and organization

Responsibilities

Design and execute appropriate upstream development experiments for generation of bioproduct active pharmaceutical ingredient including protein intermediates for bioconjugation
Provide hands-on support for troubleshooting technical issues and driving innovation projects with novel ideas and technologies
Participate in cross-functional process development teams and effectively collaborate with other groups in BR&D, Discovery, Technical services for Manufacturing and Manufacturing
Support transfer of upstream processes to pilot plant and manufacturing sites
Author technical reports and regulatory documents
Work effectively with external parties on development projects, research collaborations and outsourcing efforts
Support organizational initiatives as needed to achieve short-term and long-term departmental goals
Keep current of relevant scientific literature, new technologies/capabilities and regulatory initiatives/requirements and support their implementation, as appropriate
Ensure work is aligned with all relevant Development Quality, Regulatory, HSE, GLP and GMP requirements

Skills

Molecular Biology

Cell Culture

Upstream Process Development

Cell Line Development

Process Optimization

Bioprocess Engineering

Monoclonal Antibodies

Therapeutic Proteins

CMC Project Teams

Regulatory Submissions

Eli Lilly and Company

Develops and delivers prescription medicines globally

About Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company that focuses on discovering, developing, and delivering medicines to improve health. The company has a long history of scientific achievements, including the creation of insulin, the first life-saving treatment for diabetes. Lilly's operations involve extensive research and development to create new medications and enhance existing ones, ensuring they are safe and effective. Their products are primarily prescription medicines sold to healthcare providers for various medical conditions, including diabetes, cancer, and pain management. What sets Lilly apart from its competitors is its strong commitment to ethical practices and the protection of its products from counterfeiting. The company's goal is to enhance lives through innovative medical solutions while maintaining high standards of quality and ethics.

Indianapolis, IndianaHeadquarters

1876Year Founded

$1,180.1MTotal Funding

IPOCompany Stage

Biotechnology, HealthcareIndustries

10,001+Employees

Risks

Competition from Novo Nordisk's Ozempic may impact tirzepatide's market share.

Potential construction delays in Indiana could affect GLP-1 drug production timelines.

Regulatory challenges may hinder Kisunla's expansion in new Alzheimer's markets.

Differentiation

Eli Lilly's rich history includes the first life-saving insulin treatment.

Lilly's strategic partnerships enhance its position in neurodegenerative disease treatments.

FDA approval of Zepbound opens new therapeutic markets for sleep disorder treatments.

Upsides

Lilly's $9 billion complex in Indiana boosts GLP-1 drug production capacity.

Kisunla's approval in China expands Lilly's Alzheimer's treatment market in Asia.

Collaboration with EVA Pharma enhances Lilly's reputation as socially responsible.

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