Principal Scientist, Protein Design - In Silico Protein and Antibody Design at Johnson & Johnson

Spring House, Pennsylvania, United States

Apply Now

Not SpecifiedCompensation

Senior (5 to 8 years), Expert & Leadership (9+ years)Experience Level

Full TimeJob Type

UnknownVisa

Biotechnology, Pharmaceuticals, HealthcareIndustries

Requirements

PhD in Biomedical Engineering, Biochemistry, Computational Biology, Computer Science, Structural Biology, Biophysics, Material Science, or other related quantitative field with at least 3 years of experience
Advanced experience in computational protein modeling, design, structural biology, and biophysics
Ability to lead projects in cross-functional teams to completion in a collaborative manner
Experience in de novo protein design and sophisticated protein design techniques, such as large-scale backbone editing (e.g., fusion design, loop design/inpainting)
Strong background in computational biology
Proven track record of seeing designs through experimental testing

Responsibilities

Work closely with colleagues across the organization to design, develop, and deliver differentiated, best-in-class therapeutic molecules for a range of clinical indications spanning all therapeutic areas
Work directly with wet-lab scientists and therapeutic areas to design and optimize protein molecules for specific functions and properties, with a focus on antibody therapeutics
Collaborate with team members across Therapeutics Discovery on the planning, prioritization, and timely delivery of designs to support multiple concurrent programs
Serve as an In Silico Discovery Lead on diverse project teams
Work with ML colleagues to guide development, benchmarking, and application of pioneering generative and discriminative models
Model sophisticated biological systems using a variety of methods and tools to advise design methodology
Participate in internal and external presentations, peer-reviewed manuscripts, and conference proceedings

Skills

Protein Design

Antibody Design

In Silico Design

Molecular Design

Molecular Simulation

Drug Discovery

Computational Biology

Data Science

Machine Learning

Protein Engineering

Johnson & Johnson

Healthcare products in pharmaceuticals and devices.

About Johnson & Johnson

Johnson & Johnson operates in the healthcare sector with three main areas: pharmaceuticals, medical devices, and consumer health products. In the pharmaceuticals segment, the company develops prescription drugs for various medical conditions such as cancer and infectious diseases. The medical devices segment provides products used in surgeries and other medical procedures, while the consumer health segment offers over-the-counter products, including baby care and personal health items. Johnson & Johnson generates revenue through direct sales and partnerships, and it invests significantly in research and development to create new products that meet the needs of consumers and healthcare providers. The company stands out from competitors by emphasizing diversity, equity, and inclusion in its workplace, fostering an environment where employees can share their perspectives. Its goal is to improve patient outcomes and enhance the overall health and well-being of individuals globally.

New Brunswick, New JerseyHeadquarters

1886Year Founded

IPOCompany Stage

HealthcareIndustries

10,001+Employees

Risks

J&J faces a class action lawsuit in Australia over ineffective cold and flu medications.

Former J&J executives joining other firms could lead to increased competition.

Ongoing legal battles, like the lawsuit against Cigna, pose financial liabilities for J&J.

Differentiation

J&J operates in three segments: pharmaceuticals, medical devices, and consumer health.

The company invests heavily in R&D for innovative medical solutions and products.

J&J is committed to diversity, equity, and inclusion in its workplace culture.

Upsides

J&J's collaboration with Helsinki University Hospital focuses on value-based healthcare models.

The rise of personalized medicine offers J&J opportunities in targeted therapies.

Increased focus on digital health solutions presents expansion opportunities for J&J.

Land your dream remote job 3x faster with AI

Try Jobo Free