Arrowhead Pharmaceuticals

Develops RNAi-based therapies for diseases

Pasadena, California, United States

About Arrowhead Pharmaceuticals

Arrowhead Pharmaceuticals develops medicines aimed at treating severe diseases by targeting and silencing specific genes. The company uses RNA interference (RNAi), a natural process that reduces gene expression, to create therapies that can potentially stop or reverse diseases like cystic fibrosis and hepatitis B. Their approach involves a variety of RNA chemistries and effective delivery methods to ensure that the target genes are significantly reduced in activity. Unlike many competitors, Arrowhead focuses specifically on RNAi-based therapies, which allows them to address medical needs that are not met by existing treatments. The goal of Arrowhead Pharmaceuticals is to provide new treatment options for patients suffering from genetic disorders, leveraging their expertise and partnerships to bring these therapies to market.

Pasadena, CaliforniaHeadquarters
2004Year Founded
$4.7MTotal Funding
IPOCompany Stage
Biotechnology, HealthcareIndustries
51-200Employees

Benefits

Health Insurance
Dental Insurance
Vision Insurance
Life Insurance
Disability Insurance
401(k) Retirement Plan
Paid Vacation
Paid Sick Leave

Risks

Increased competition from companies like Alnylam Pharmaceuticals in the RNAi space.
Potential regulatory scrutiny could delay clinical trials for RNAi therapies.
Financial instability risk due to reliance on strategic financing agreements.

Differentiation

Arrowhead uses RNAi to target and silence disease-causing genes effectively.
The company has a broad portfolio of RNA chemistries for diverse therapeutic applications.
Arrowhead's strategic partnerships enhance its research and development capabilities.

Upsides

Arrowhead secured a $500 million facility with Sixth Street for pipeline advancement.
Positive Phase 2 data for plozasiran shows promise in treating severe hypertriglyceridemia.
Collaboration with Sarepta Therapeutics brings significant financial and research benefits.

Funding

Total raised$4.67 M
Latest valuation$10.00 M
StageIPO
EARLY VC
7/31/2010
$2
$10.00 M